Ida Sim, PhD, MD

Professor

Ida Sim, MD, PhD is a primary care physician, informatics researcher, and entrepreneur. She is a Professor of Medicine (UCSF) and Computational Precision Health (UCSF and UC Berkeley) and is Co-Director of the UCSF UC Berkeley Joint Program in Computational Precision Health. In 2023, Dr. Sim became UCSF's inaugural Chief Research Informatics Officer.

Dr. Sim is a global leader in the technology and policy of large-scale health data sharing. She is co-founder of the Open mHealth/IEEE 1752 family of global mobile health data standards. In 2019, she co-developed CommonHealth, an open-source software suite bringing to the Android ecosystem the equivalent of Apple Health's ability to access and share EHR data. Most recently, she is co-lead of the JupyterHealth project, which combines OpenmHealth, CommonHealth, and Project Jupyter to transform the digital and precision health ecosystem.

Dr. Sim is also co-founder of Vivli, the world's largest data-sharing platform for participant-level clinical trial data. In 2005, she was the founding Project Coordinator of the World Health Organization's International Clinical Trials Registry Platform, where she led the establishment of the first global policy on clinical trial registration.

Dr. Sim has led multiple NIH, AHRQ, and NSF grants and has served on multiple advisory committees on health information infrastructure for clinical care and research, including committees of the National Research Council and National Academy of Medicine. She is a recipient of the United States Presidential Early Career Award for Scientists and Engineers (PECASE), a member of the National Academy of Medicine, a Fellow of the American College of Medical Informatics, and a member of the American Society for Clinical Investigation.
Education
1997 - Fellowship, Health Services Research, Stanford University
PhD, 1997 - Medical Informatics, Stanford University
1993 - Primary Care Internal Medicine Residency, Massachussetts General Hospital
M.D., 1990 - , Stanford University
Honors and Awards
  • Luminary Award, Precision Medicine World Conference, 2025
  • STATUS2024 Health Science Leader, STAT News, 2024
  • Elected Member, National Academy of Medicine, 2022
  • Elected Member, American Society for Clinical Investigation, 2010
  • Elected Fellow, American College of Medial Informatics, 2007
  • Leadership Award, American Medical Informatics Association, 2005
  • United States Presidential Early Career Award for Scientists and Engineers, White House Office of Science Technology and Policy, 2000
Websites
  • Home
  • Home – GREI
Publications

  2. Horwitz RI, Otaka SN, Conroy AH, Cullen MR, Matory A, Singer BH, Sim I. Biosocial Variation in Treatment Response to GLP-1s: Implications for Clinical Care and Health Policy. 2025. PMID: 40393609


  3. Idnay B, Xu Z, Adams WG, Adibuzzaman M, Anderson NR, Bahroos N, Bell DS, Bumgardner C, Campion T, Castro M, Cimino JJ, Cohen IG, Dorr D, Elkin PL, Fan JW, Ferris T, Foran DJ, Hanauer D, Hogarth M, Huang K, Kalpathy-Cramer J, Kandpal M, Karnik NS, Katoch A, Lai AM, Lambert CG, Li L, Lindsell C, Liu J, Lu Z, Luo Y, McGarvey P, Mendonca EA, Mirhaji P, Murphy S, Osborne JD, Paschalidis IC, Harris PA, Prior F, Shaheen NJ, Shara N, Sim I, Tachinardi U, Waitman LR, Wright RJ, Zai AH, Zheng K, Lee SS, Malin BA, Natarajan K, Price Ii WN, Zhang R, Zhang Y, Xu H, Bian J, Weng C, Peng Y. Environment scan of generative AI infrastructure for clinical and translational science. 2025. PMID: 39872195


  4. Meghana Gadgil, Rose Pavlakos, Simona Carini, Brian Turner, Ileana Elder, William Hess, Lisa Houle, Lavonia Huff, Elaine Johanson, Carole Jones, Daphne Liang, Pamela Ogonowski, Joshua Phipps, Tyler Peryea, Ida Sim. Automating Individualized Notification of Drug Recalls to Patients: Complex Challenges and Qualitative Evaluation (Preprint). 2024. PMID:


  5. Ralph I. Horwitz, Mark R. Cullen, Allison Hayes Conroy, Ida Sim, Burton H. Singer, Kimberly Badal, Emanuela Offidani. Integrating biology and biography in medicine: The mind and body are not separate. 2024. PMID:


  7. Block VJ, Koshal K, Wijangco J, Miller N, Sara N, Henderson K, Reihm J, Gopal A, Mohan SD, Gelfand JM, Guo CY, Oommen L, Nylander A, Rowson JA, Brown E, Sanders S, Rankin K, Lyles CR, Sim I, Bove R. A Closed-Loop Falls Monitoring and Prevention App for Multiple Sclerosis Clinical Practice: Human-Centered Design of the Multiple Sclerosis Falls InsightTrack. 2024. PMID: 38206662


  8. Arvisais-Anhalt S, Ravi A, Weia B, Aarts J, Ahmad HB, Araj E, Bauml JA, Benham-Hutchins M, Boyd AD, Brecht-Doscher A, Butler-Henderson K, Butte A, Cardillo AB, Chilukuri N, Cho MK, Cohen JK, Craven CK, Crusco SJ, Dadabhoy F, Dash D, DeBolt C, Elkin PL, Fayanju OA, Fochtmann L, Graham JV, Hanna J, Hersh W, Hoffard MR, Hron J, Huang SS, Jackson BR, Kaplan B, Kelly W, Ko K, Koppel R, Kurapati N, Labbad G, Lee J, Lehmann CU, Leitner S, Liao ZC, Medford RJ, Melnick ER, Muniyappa AN, Murray S, Neinstein A, Nichols-Johnson V, Novak L, Ogan WS, Ozeran L, Pageler N, Pandita D, Perumbeti A, Petersen C, Pierce L, Puttagunta R, Ramaswamy P, Rogers KM, Rosenbloom T, Ryan A, Saleh S, Sarabu C, Schreiber R, Shaw KA, Sim I, Sirintrapun SJ, Solomonides A, Spector JD, Starren JB, Stoffel M, Subbian V, Swanson K, Tomes A, Trang K, Unertl KM, Weon JL, Whooley M, Wiley K, Williamson DF, Winkelstein P, Wong J, Xie J, Yarahuan JKW, Yung N, Zera C, Ratanawongsa N, Sadasivaiah S. Paging the Clinical Informatics Community: Respond STAT to Dobbs v Jackson's Women's Health Organization. 2022. PMID: 36535703


  9. Ida Sim, Marina Sirota. Data and Computation: A Contemporary Landscape. 2022. PMID:


  10. Liu H, Carini S, Chen Z, Phillips Hey S, Sim I, Weng C. Ontology-based categorization of clinical studies by their conditions. 2022. PMID: 36283581


  12. Horwitz RI, Hayes-Conroy A, Singer BH, Cullen MR, Badal K, Sim I. Falling down the biological rabbit hole: Epstein-Barr virus, biography, and multiple sclerosis. 2022. PMID: 36047497


  13. Ida Sim. Data Sharing and Reuse. 2022. PMID:


  14. Horwitz RI, Conroy AH, Cullen MR, Colella K, Mawn M, Singer BH, Sim I. Long COVID and Medicine's Two Cultures. 2022. PMID: 35417745


  15. Larson K, Sim I, von Isenburg M, Levenstein M, Rockhold F, Neumann S, D'Arcy C, Graham E, Zuckerman D, Li R. COVID-19 interventional trials: Analysis of data sharing intentions during a time of pandemic. 2022. PMID: 35182738


  16. Zeng B, Bove R, Carini S, Lee JS, Pollak JP, Schleimer E, Sim I. Standardized Integration of Person-Generated Data Into Routine Clinical Care. 2022. PMID: 35142627


  17. Horwitz RI, Singer BH, Hayes-Conroy A, Cullen MR, Mawn M, Colella K, Sim I. Biosocial Pathogenesis. 2022. PMID: 35104822


  18. Marcus GM, Modrow MF, Schmid CH, Sigona K, Nah G, Yang J, Chu TC, Joyce S, Gettabecha S, Ogomori K, Yang V, Butcher X, Hills MT, McCall D, Sciarappa K, Sim I, Pletcher MJ, Olgin JE. Individualized Studies of Triggers of Paroxysmal Atrial Fibrillation: The I-STOP-AFib Randomized Clinical Trial. 2021. PMID: 34775507


  19. Wang EY, Breyer BN, Lee AW, Rios N, Oni-Orisan A, Steinman MA, Sim I, Kenfield SA, Bauer SR. Perceptions of Older Men Using a Mobile Health App to Monitor Lower Urinary Tract Symptoms and Tamsulosin Side Effects: Mixed Methods Study. 2021. PMID: 34951599


  20. Lee AW, Kenfield SA, Wang EY, Enriquez A, Oni-Orisan A, Steinman MA, Sim I, Breyer BN, Bauer SR. Tracking Lower Urinary Tract Symptoms and Tamsulosin Side Effects Among Older Men Using a Mobile App (PERSONAL): Feasibility and Usability Study. 2021. PMID: 34889745


  21. Horwitz RI, Lobitz G, Mawn M, Conroy AH, Cullen MR, Sim I, Singer BH. Rethinking Table 1. 2021. PMID: 34800675


  22. Sim I, Cassel C. HIPAA and the Leak of "Deidentified" EHR Data. 2021. PMID: 34525298


  23. Elizabeth Y. Wang, Benjamin N. Breyer, Austin Lee, Natalie Rios, Akinyemi Oni-Orisan, Michael A. Steinman, Ida Sim, Stacey A. Kenfield, Scott R. Bauer. MP28-03 PERCEPTIONS OF OLDER MEN USING A MOBILE HEALTH APPLICATION TO MONITOR LOWER URINARY TRACT SYMPTOMS AND TAMSULOSIN ADVERSE EFFECTS: MIXED-METHODS STUDY. 2021. PMID:


  24. Kravitz RL, Marois M, Sim I, Ward D, Kanekar S, Yu A, Dounias P, Yang J, Wang Y, Schmid CH. Chronic Pain Treatment Preferences Change Following Participation in N-of-1 Trials, but not Always in the Expected Direction. 2021. PMID: 34400254


  25. Horwitz RI, Lobitz G, Mawn M, Conroy AH, Cullen MR, Sim I, Singer BH. Biosocial medicine: Biology, biography, and the tailored care of the patient. 2021. PMID: 34430699


  26. Coetzee T, Ball MP, Boutin M, Bronson A, Dexter DT, English RA, Furlong P, Goodman AD, Grossman C, Hernandez AF, Hinners JE, Hudson L, Kennedy A, Marchisotto MJ, Matrisian L, Myers E, Nowell WB, Nosek BA, Sherer T, Shore C, Sim I, Smolensky L, Williams C, Wood J, Terry SF. Correction: Data Sharing Goals for Nonprofit Funders of Clinical Trials. 2021. PMID: 34255670


  27. Ku JP, Sim I. Mobile Health: making the leap to research and clinics. 2021. PMID: 33990671


  30. Bent B, Sim I, Dunn JP. Digital Medicine Community Perspectives and Challenges: Survey Study. 2021. PMID: 33533721


  31. Li R, Wood J, Baskaran A, Neumann S, Graham E, Levenstein M, Sim I. Timely access to trial data in the context of a pandemic: the time is now. 2020. PMID: 33122319


  33. Kury F, Butler A, Yuan C, Fu LH, Sun Y, Liu H, Sim I, Carini S, Weng C. Chia, a large annotated corpus of clinical trial eligibility criteria. 2020. PMID: 32855408


  34. Bent B, Wang K, Grzesiak E, Jiang C, Qi Y, Jiang Y, Cho P, Zingler K, Ogbeide FI, Zhao A, Runge R, Sim I, Dunn J. The digital biomarker discovery pipeline: An open-source software platform for the development of digital biomarkers using mHealth and wearables data. 2020. PMID: 33948242


  35. Bauer SR, Breyer BN, Oni-Orisan A, Steinman MA, Sim I, McCulloch CE, Kenfield SA. PERSONAL: Feasibility Study Protocol for Placebo-Controlled, Randomized n-of-1 Trials of Tamsulosin for Lower Urinary Tract Symptoms. 2020. PMID: 34713020


  36. Kravitz RL, Aguilera A, Chen EJ, Choi YK, Hekler E, Karr C, Kim KK, Phatak S, Sarkar S, Schueller SM, Sim I, Yang J, Schmid CH. Feasibility, Acceptability, and Influence of mHealth-Supported N-of-1 Trials for Enhanced Cognitive and Emotional Well-Being in US Volunteers. 2020. PMID: 32695740


  37. Ida Sim. Data Sharing and Reuse. 2020. PMID:


  38. Sim I, Stebbins M, Bierer BE, Butte AJ, Drazen J, Dzau V, Hernandez AF, Krumholz HM, Lo B, Munos B, Perakslis E, Rockhold F, Ross JS, Terry SF, Yamamoto KR, Zarin DA, Li R. Time for NIH to lead on data sharing. Volume 367 of Issue 6484. 2020. PMID: 32193313


  39. Sim I. Mobile Devices and Health. Volume 381 of Issue 10. 2019. PMID: 31483966


  40. Li R, Sim I. How Clinical Trial Data Sharing Platforms Can Advance the Study of Biomarkers. Volume 47 of Issue 3. 2019. PMID: 31560635


  41. Odineal DD, Marois MT, Ward D, Schmid CH, Cabrera R, Sim I, Wang Y, Wilsey B, Duan N, Henry SG, Kravitz RL. Effect of Mobile Device-Assisted N-of-1 Trial Participation on Analgesic Prescribing for Chronic Pain: Randomized Controlled Trial. Volume 35 of Issue 1. 2019. PMID: 31463686


  42. Hekler EB, Klasnja P, Chevance G, Golaszewski NM, Lewis D, Sim I. Why we need a small data paradigm. Volume 17 of Issue 1. 2019. PMID: 31311528


  43. Li T, Saldanha IJ, Jap J, Smith BT, Canner J, Hutfless SM, Branch V, Carini S, Chan W, de Bruijn B, Wallace BC, Walsh SA, Whamond EJ, Murad MH, Sim I, Berlin JA, Lau J, Dickersin K, Schmid CH. A randomized trial provided new evidence on the accuracy and efficiency of traditional vs. electronically annotated abstraction approaches in systematic reviews. Volume 115. 2019. PMID: 31302205


  44. Zhang X, Hailu B, Tabor DC, Gold R, Sayre MH, Sim I, Jean-Francois B, Casnoff CA, Cullen T, Thomas VA, Artiles L, Williams K, Le PT, Aklin CF, James R. Role of Health Information Technology in Addressing Health Disparities: Patient, Clinician, and System Perspectives. Volume 57 Suppl 6 Suppl 2. 2019. PMID: 31095049


  45. Kravitz RL, Sim I, Duan N. A Case for n-of-1 Trials-Reply. Volume 179 of Issue 3. 2019. PMID: 30830192


  46. Kravitz RL, Schmid CH, Sim I. Finding Benefit in n-of-1 Trials-Reply. Volume 179 of Issue 3. 2019. PMID: 30830195


  47. Fukushima M, Austin C, Sato N, Maruyama T, Navarro E, Rocca M, Demotes J, Haendel M, Volchenboum SL, Cowperthwaite M, Silverstein JC, Webb C, Sim I, Chase M, Speakman J, Augustine E, Ford DE, Kush R. The Global academic research organization network: Data sharing to cure diseases and enable learning health systems. Volume 3 of Issue 1. 2018. PMID: 31245596


  48. Rebecca Li, Jessica Scott, Frank Rockhold, Nina Hill, Julie Wood, Ida Sim. Moving Data Sharing Forward: The Launch of the Vivli Platform. 2018. PMID:


  49. Whitney RL, Ward DH, Marois MT, Schmid CH, Sim I, Kravitz RL. Patient Perceptions of Their Own Data in mHealth Technology-Enabled N-of-1 Trials for Chronic Pain: Qualitative Study. Volume 6 of Issue 10. 2018. PMID: 30309834


  50. Kravitz RL, Schmid CH, Marois M, Wilsey B, Ward D, Hays RD, Duan N, Wang Y, MacDonald S, Jerant A, Servadio JL, Haddad D, Sim I. Effect of Mobile Device-Supported Single-Patient Multi-crossover Trials on Treatment of Chronic Musculoskeletal Pain: A Randomized Clinical Trial. Volume 178 of Issue 10. 2018. PMID: 30193253


  51. Kumar S, Abowd G, Abraham WT, al'Absi M, Chau DHP, Ertin E, Estrin D, Ganesan D, Hnat T, Hossain SM, Ives Z, Kerr J, Marlin BM, Murphy S, Rehg JM, Nahum-Shani I, Shetty V, Sim I, Spring B, Srivastava M, Wetter D. Center of Excellence for Mobile Sensor Data-to-Knowledge (MD2K). Volume 16 of Issue 2. 2017. PMID: 29276451


  52. Saldanha IJ, Schmid CH, Lau J, Dickersin K, Berlin JA, Jap J, Smith BT, Carini S, Chan W, De Bruijn B, Wallace BC, Hutfless SM, Sim I, Murad MH, Walsh SA, Whamond EJ, Li T. Evaluating Data Abstraction Assistant, a novel software application for data abstraction during systematic reviews: protocol for a randomized controlled trial. Volume 5 of Issue 1. 2016. PMID: 27876082


  53. Bierer BE, Li R, Barnes M, Sim I. A Global, Neutral Platform for Sharing Trial Data. Volume 374 of Issue 25. 2016. PMID: 27168194


  55. He Z, Ryan P, Hoxha J, Wang S, Carini S, Sim I, Weng C. Multivariate analysis of the population representativeness of related clinical studies. Volume 60. 2016. PMID: 26820188


  56. Elliott JH, Grimshaw J, Altman R, Bero L, Goodman SN, Henry D, Macleod M, Tovey D, Tugwell P, White H, Sim I. Informatics: Make sense of health data. Volume 527 of Issue 7576. 2015. PMID: 26536942


  57. Kumar S, Abowd GD, Abraham WT, al'Absi M, Beck JG, Chau DH, Condie T, Conroy DE, Ertin E, Estrin D, Ganesan D, Lam C, Marlin B, Marsh CB, Murphy SA, Nahum-Shani I, Patrick K, Rehg JM, Sharmin M, Shetty V, Sim I, Spring B, Srivastava M, Wetter DW. Center of excellence for mobile sensor data-to-knowledge (MD2K). Volume 22 of Issue 6. 2015. PMID: 26555017


  58. Barr C, Marois M, Sim I, Schmid CH, Wilsey B, Ward D, Duan N, Hays RD, Selsky J, Servadio J, Schwartz M, Dsouza C, Dhammi N, Holt Z, Baquero V, MacDonald S, Jerant A, Sprinkle R, Kravitz RL. The PREEMPT study - evaluating smartphone-assisted n-of-1 trials in patients with chronic pain: study protocol for a randomized controlled trial. Volume 16. 2015. PMID: 25881274


  59. He Z, Carini S, Sim I, Weng C. Visual aggregate analysis of eligibility features of clinical trials. Volume 54. 2015. PMID: 25615940


  60. Ross J, Neylan T, Weiner M, Chao L, Samuelson K, Sim I. Towards Constructing a New Taxonomy for Psychiatry Using Self-reported Symptoms. Volume 216. 2015. PMID: 26262149


  61. He Z, Carini S, Hao T, Sim I, Weng C. A method for analyzing commonalities in clinical trial target populations. Volume 2014. 2014. PMID: 25954450


  62. Brennan PF, Valdez R, Alexander G, Arora S, Bernstam EV, Edmunds M, Kirienko N, Martin RD, Sim I, Skiba D, Rosenbloom T. Patient-centered care, collaboration, communication, and coordination: a report from AMIA's 2013 Policy Meeting. Volume 22 of Issue e1. 2014. PMID: 25359545


  63. DePasse JW, Chen CE, Sawyer A, Jethwani K, Sim I. Academic Medical Centers as digital health catalysts. Volume 2 of Issue 3. 2014. PMID: 26250503


  64. Sim I, Tu SW, Carini S, Lehmann HP, Pollock BH, Peleg M, Wittkowski KM. The Ontology of Clinical Research (OCRe): an informatics foundation for the science of clinical research. Volume 52. 2013. PMID: 24239612


  65. Cohen AM, Demner-Fushman D, Iorio A, Sim I, Smalheiser NR. Tools for Identifying Reliable Evidence and Implementing it in Everyday Clinical Care. 2013. PMID: 24303233


  66. Roumiantseva D, Carini S, Sim I, Wagner TH. Sponsorship and design characteristics of trials registered in ClinicalTrials.gov. Volume 34 of Issue 2. 2013. PMID: 23380028


  67. Ochs C, Agrawal A, Perl Y, Halper M, Tu SW, Carini S, Sim I, Noy N, Musen M, Geller J. Deriving an abstraction network to support quality assurance in OCRe. Volume 2012. 2012. PMID: 23304341


  68. Sim I, Carini S, Tu SW, Detwiler LT, Brinkley J, Mollah SA, Burke K, Lehmann HP, Chakraborty S, Wittkowski KM, Pollock BH, Johnson TM, Huser V. Ontology-based federated data access to human studies information. Volume 2012. 2012. PMID: 23304360


  69. Chen C, Haddad D, Selsky J, Hoffman JE, Kravitz RL, Estrin DE, Sim I. Making sense of mobile health data: an open architecture to improve individual- and population-level health. Volume 14 of Issue 4. 2012. PMID: 22875563


  70. Boland MR, Tu SW, Carini S, Sim I, Weng C. EliXR-TIME: A Temporal Knowledge Representation for Clinical Research Eligibility Criteria. Volume 2012. 2012. PMID: 22779055


  71. Ida Sim, Joyce C. Niland. Study Protocol Representation. 2012. PMID:


  72. Susan Graham, Deborah Estrin, Eric Horvitz, Isaac Kohane, Elizabeth Mynatt, Ida Sim. Information Technology research challenges for healthcare: from discovery to delivery. 2011. PMID:


  73. Bhavnani SK, Carini S, Ross J, Sim I. Network analysis of clinical trials on depression: implications for comparative effectiveness research. Volume 2010. 2010. PMID: 21346939


  74. Estrin D, Sim I. Health care delivery. Open mHealth architecture: an engine for health care innovation. Volume 330 of Issue 6005. 2010. PMID: 21051617


  75. Kiritchenko S, de Bruijn B, Carini S, Martin J, Sim I. ExaCT: automatic extraction of clinical trial characteristics from journal publications. Volume 10. 2010. PMID: 20920176


  76. Tu SW, Peleg M, Carini S, Bobak M, Ross J, Rubin D, Sim I. A practical method for transforming free-text eligibility criteria into computable criteria. Volume 44 of Issue 2. 2010. PMID: 20851207


  77. Ross J, Tu S, Carini S, Sim I. Analysis of eligibility criteria complexity in clinical trials. Volume 2010. 2010. PMID: 21347148


  78. Wynden R, Weiner MG, Sim I, Gabriel D, Casale M, Carini S, Hastings S, Ervin D, Tu S, Gennari JH, Anderson N, Mobed K, Lakshminarayanan P, Massary M, Cucina RJ. Ontology mapping and data discovery for the translational investigator. Volume 2010. 2010. PMID: 21347152


  79. Sim I, Carini S, Tu S, Wynden R, Pollock BH, Mollah SA, Gabriel D, Hagler HK, Scheuermann RH, Lehmann HP, Wittkowski KM, Nahm M, Bakken S. The human studies database project: federating human studies design data using the ontology of clinical research. Volume 2010. 2010. PMID: 21347149


  80. Weng C, Tu SW, Sim I, Richesson R. Formal representation of eligibility criteria: a literature review. Volume 43 of Issue 3. 2009. PMID: 20034594


  81. Carini S, Pollock BH, Lehmann HP, Bakken S, Barbour EM, Gabriel D, Hagler HK, Harper CR, Mollah SA, Nahm M, Nguyen HH, Scheuermann RH, Sim I. Development and evaluation of a study design typology for human research. Volume 2009. 2009. PMID: 20351827


  82. Moja LP, Moschetti I, Nurbhai M, Compagnoni A, Liberati A, Grimshaw JM, Chan AW, Dickersin K, Krleza-Jeric K, Moher D, Sim I, Volmink J. Compliance of clinical trial registries with the World Health Organization minimum data set: a survey. Volume 10. 2009. PMID: 19624821


  83. Bernstam EV, Hersh WR, Johnson SB, Chute CG, Nguyen H, Sim I, Nahm M, Weiner MG, Miller P, DiLaura RP, Overcash M, Lehmann HP, Eichmann D, Athey BD, Scheuermann RH, Anderson N, Starren J, Harris PA, Smith JW, Barbour E, Silverstein JC, Krusch DA, Nagarajan R, Becich MJ. Synergies and distinctions between computational disciplines in biomedical research: perspective from the Clinical andTranslational Science Award programs. Volume 84 of Issue 7. 2009. PMID: 19550198


  84. Bernstam EV, Hersh WR, Sim I, Eichmann D, Silverstein JC, Smith JW, Becich MJ. Unintended consequences of health information technology: a need for biomedical informatics. Volume 43 of Issue 5. 2009. PMID: 19508898


  85. Sim I, Chute CG, Lehmann H, Nagarajan R, Nahm M, Scheuermann RH. Keeping raw data in context. Volume 323 of Issue 5915. 2009. PMID: 19197039


  86. Karp PD, Sherlock G, Gerlt JA, Sim I, Paulsen I, Babbitt PC, Laderoute K, Hunter L, Sternberg P, Wooley J, Bourne PE. Changes to NIH grant system may backfire. Volume 322 of Issue 5905. 2008. PMID: 19023064


  87. Hernandez ME, Carini S, Storey MA, Sim I. An interactive tool for visualizing design heterogeneity in clinical trials. 2008. PMID: 18998925


  88. de Bruijn B, Carini S, Kiritchenko S, Martin J, Sim I. Automated information extraction of key trial design elements from clinical trial publications. 2008. PMID: 18999067


  89. Speedie SM, Taweel A, Sim I, Arvanitis TN, Arvanitis T, Delaney B, Peterson KA. Characterizing primary care research: PCROM versus BRIDG. 2008. PMID: 18998919


  90. Lee K, Bacchetti P, Sim I. Publication of clinical trials supporting successful new drug applications: a literature analysis. Volume 5 of Issue 9. 2008. PMID: 18816163


  91. Speedie SM, Taweel A, Sim I, Arvanitis TN, Delaney B, Peterson KA. The Primary Care Research Object Model (PCROM): a computable information model for practice-based primary care research. Volume 15 of Issue 5. 2008. PMID: 18579829


  92. Ghersi D, Clarke M, Berlin J, Gülmezoglu A, Kush R, Lumbiganon P, Moher D, Rockhold F, Sim I, Wager E. Reporting the findings of clinical trials: a discussion paper. Volume 86 of Issue 6. 2008. PMID: 18568282


  93. Sim I. Trial registration for public trust: making the case for medical devices. Volume 23 Suppl 1. 2008. PMID: 18095047


  94. Krleza-Jeric K, Chan AW, Dickersin K, Sim I, Grimshaw J, Gluud C. [Principles of the international registry of protocols and clinical trial results based on health interventions in human beings: Ottawa Declaration (part 1)]. Volume 19 of Issue 6. 2006. PMID: 16968596


  95. Sim I, Chan AW, Gülmezoglu AM, Evans T, Pang T. Clinical trial registration: transparency is the watchword. Volume 367 of Issue 9523. 2006. PMID: 16714166


  96. Chan AW, Sim I, Gülmezoglu AM, Unterlerchner P, Karam G, Pang T. Assessing clinical trial results. Volume 312 of Issue 5772. 2006. PMID: 16634140


  97. Gülmezoglu AM, Sim I. International clinical trial registration: any progress? Volume 118 of Issue 1-2. 2006. PMID: 16489516


  98. Berlin A, Sorani M, Sim I. A taxonomic description of computer-based clinical decision support systems. Volume 39 of Issue 6. 2006. PMID: 16442854


  99. Rubin DL, Lewis SE, Mungall CJ, Misra S, Westerfield M, Ashburner M, Sim I, Chute CG, Solbrig H, Storey MA, Smith B, Day-Richter J, Noy NF, Musen MA. National Center for Biomedical Ontology: advancing biomedicine through structured organization of scientific knowledge. Volume 10 of Issue 2. 2006. PMID: 16901225


  101. Sim I, Detmer DE. Beyond trial registration: a global trial bank for clinical trial reporting. Volume 2 of Issue 11. 2005. PMID: 16220999


  102. Miller RH, West C, Brown TM, Sim I, Ganchoff C. The value of electronic health records in solo or small group practices. Volume 24 of Issue 5. 2005. PMID: 16162555


  103. Krleza-Jeric K, Chan AW, Dickersin K, Sim I, Grimshaw J, Gluud C. Principles for international registration of protocol information and results from human trials of health related interventions: Ottawa statement (part 1). Volume 330 of Issue 7497. 2005. PMID: 15845980


  104. Sim I, Cummings SR. Quantifying the gap between proof and practice. Volume 8 of Issue 4. 2004. PMID: 16379955


  106. Miller RH, Sim I. Physicians' use of electronic medical records: barriers and solutions. Volume 23 of Issue 2. 2004. PMID: 15046136


  107. Berlin A, Sorani M, Sim I. Characteristics of outpatient clinical decision support systems: a taxonomic description. Volume 107 of Issue Pt 1. 2004. PMID: 15360878


  108. Miller RH, Sim I, Newman J. Electronic medical records in solo/small groups: a qualitative study of physician user types. Volume 107 of Issue Pt 1. 2004. PMID: 15360895


  109. Cuadros J, Sim I. EyePACS: an open source clinical communication system for eye care. Volume 107 of Issue Pt 1. 2004. PMID: 15360804


  110. Sim I, Carini S, Olasov B, Jeng S. Trial bank publishing: phase I results. Volume 107 of Issue Pt 2. 2004. PMID: 15361060


  111. Sim I, Cummings SR. A new framework for describing and quantifying the gap between proof and practice. Volume 41 of Issue 8. 2003. PMID: 12886168


  112. Sim I, Berlin A. A framework for classifying decision support systems. 2003. PMID: 14728243


  116. Linder JA, Sim I. Antibiotic treatment of acute bronchitis in smokers: a systematic review. Volume 17 of Issue 3. 2002. PMID: 11929510


  117. Sim I, Gorman P, Greenes RA, Haynes RB, Kaplan B, Lehmann H, Tang PC. Clinical decision support systems for the practice of evidence-based medicine. 2001. PMID: 11687560


  118. Sim I, Owens DK, Lavori PW, Rennels GD. Electronic trial banks: a complementary method for reporting randomized trials. Volume 20 of Issue 4. 2000. PMID: 11059477


  119. Sim I, Lavori P. Meta-analyses and large randomized, controlled trials. Volume 338 of Issue 1. 1998. PMID: 9424568


  120. Sim I, McDonald KM, Lavori PW, Norbutas CM, Hlatky MA. Quantitative overview of randomized trials of amiodarone to prevent sudden cardiac death. Volume 96 of Issue 9. 1997. PMID: 9386144


  121. Sim I, Hlatky MA. Growing pains of meta-analysis. Volume 313 of Issue 7059. 1996. PMID: 8819428


  124. Sim I, Rennels G. A trial bank model for the publication of clinical trials. 1995. PMID: 8563415


  126. Burcham TS, Sim I, Bolin LM, Shooter EM. The NGF complex from the African rat Mastomys natalensis. Volume 16 of Issue 6. 1991. PMID: 1791910


  127. Manchand PS, Cerruti RL, Martin JA, Hill CH, Merrett JH, Keech E, Belshe RB, Connell EV, Sim IS. Synthesis and antiviral activity of metabolites of rimantadine. Volume 33 of Issue 7. 1990. PMID: 2362279


  128. Lepock JR, Cheng KH, Al-Qysi H, Sim I, Koch CJ, Kruuv J. Hyperthermia-induced inhibition of respiration and mitochondrial protein denaturation in CHL cells. Volume 3 of Issue 2. 1987. PMID: 3036971


  129. Frankfurt M, Siegel RA, Sim I, Wuttke W. Estrous cycle variations in cholecystokinin and substance P concentrations in discrete areas of the rat brain. Volume 42 of Issue 3. 1986. PMID: 2419781


  130. Frankfurt M, Siegel RA, Sim I, Wuttke W. Cholecystokinin and substance P concentrations in discrete areas of the rat brain: sex differences. Volume 358 of Issue 1-2. 1985. PMID: 2416392